Publications

For more publications please visit: https://profiles.ucsd.edu/jack.bui

1. Activated T cell extracellular vesicle DNA transfer enhances antigen presentation and anti-tumor immunity. Cancer Cell. 2026 May 11; 44(5):965-982.e12. Hu M, Liu DA, Wortzel I, Collier P, Nelson TM, Foox J, Zhong G, Tobias G, Asao T, Bojmar L, Kenific CM, Wang G, Caielli S, Wan Z, Qureshy S, Reed M, Piszczatowski R, Ravisankar P, Brown JA, Xiong S, Wang H, Lauritzen P, Aylon Y, Molina H, Jarnagin WR, Oren M, Stanger BZ, Bui J, Bergers G, Noël A, Grandgenett PM, Hollingsworth MA, Tuveson D, Boudreau N, Bromberg J, Kelsen D, Jones DR, Santambrogio L, Zeng MY, Pascual V, Kim HS, Mason CE, Zhang H, Matei IR, Lyden D. PMID: 42066762; PMCID: PMC13215210.

2. Derivation of functional early gestation decidual natural killer cell subtypes from induced pluripotent stem cells. Stem Cells. 2026 Apr 17. Chu Cheung V, Jaimez J, DaCosta C, Arora H, Caron C, Slamecka J, Fierro M, Meads M, Fisch K, Morey RE, Cruz LS, Pant D, Kaufman DS, Horii M, Bui JD, Parast MM. PMID: 41999228.

3. Interferons as therapeutic orchestrators of cancer stem cell plasticity and therapy response. Cytokine Growth Factor Rev. 2025 Dec 15; 87:102-112. Kasat D, Hidalgo S, Wang L, Bui JD, Dosset M. PMID: 41421236.

4. Identification Of Protein Cargo in Extracellular Vesicles from Macrophages in Progressing and Regressing Tumors. bioRxiv. 2025 Nov 06. Zhu Y, Cai J, Suhandynata RT, Bui JD. PMID: 41279039; PMCID: PMC12637521.

5. Derivation of functional early gestation decidual natural killer cell subtypes from induced pluripotent stem cells. bioRxiv. 2025 Nov 05. Cheung VC, DaCosta C, Jaimez J, Arora H, Caron C, Slamecka J, Fierro M, Meads M, Fisch K, Morey RE, Pant D, Kaufman DS, Horii M, Bui JD, Parast MM. PMID: 41279445; PMCID: PMC12637421.

6. RGI-2001 for the prophylaxis of acute graft-versus-host disease after allogeneic HCT. Blood. 2025 Oct 23; 146(17):2037-2046. DeFilipp Z, Choe H, Efebera YA, Saad A, Farhan S, Lekakis L, Yared JA, Schiller G, Mapara MY, Assal A, Gooley T, Bui JD, Lee D, Lane H, Chen YB. PMID: 40680268.

7. Mammary tissue microbiome analysis in PyMT mice reveals Methylobacteria as a commensal organism with potential therapeutic applications. Transl Oncol. 2025 Sep; 59:102451. Chan AA, Caron C, Navarrete M, Lee CK, Noguti J, Bui JD, Lee DJ. PMID: 40570700; PMCID: PMC12302725.

8. Mutant prion protein enhances NMDA receptor activity, activates PKC, and triggers rapid excitotoxicity in mice. J Clin Invest. 2025 Apr 04. Lin J, Callender JA, Mayfield JE, McClatchy DB, Ojeda-Juárez D, Pourhamzeh M, Soldau K, Kurt TD, Danque GA, Khuu H, Ronson JE, Pizzo DP, Du Y, Gruber MA, Sevillano AM, Wang J, Orrú CD, Chen J, Funk G, Aguilar-Calvo P, Aulston BD, Roy S, Rho JM, Bui JD, Newton AC, Lipton SA, Caughey B, Patrick GN, Doré K, Yates JR, Sigurdson CJ. PMID: 40185484.

9. Mutant prion protein enhances NMDA receptor activity, activates PKC, and triggers rapid excitotoxicity in mice. J Clin Invest. 2025 May 15; 135(10). Lin J, Callender JA, Mayfield JE, McClatchy DB, Ojeda-Juárez D, Pourhamzeh M, Soldau K, Kurt TD, Danque GA, Khuu H, Ronson JE, Pizzo DP, Du Y, Gruber MA, Sevillano AM, Wang J, Orrú CD, Chen J, Funk G, Aguilar-Calvo P, Aulston BD, Roy S, Rho JM, Bui JD, Newton AC, Lipton SA, Caughey B, Patrick GN, Doré K, Yates JR, Sigurdson CJ. PMID: 40185484; PMCID: PMC12077891.

10. Functional differences between rodent and human PD-1 linked to evolutionary divergence. Sci Immunol. 2025 01 03; 10(103):eads6295. Masubuchi T, Chen L, Marcel N, Wen GA, Caron C, Zhang J, Zhao Y, Morris GP, Chen X, Hedrick SM, Lu LF, Wu C, Zou Z, Bui JD, Hui E. PMID: 39752535; PMCID: PMC11774210.

11. MAP kinase kinase 1 (MEK1) within extracellular vesicles inhibits tumour growth by promoting anti-tumour immunity. J Extracell Vesicles. 2024 10; 13(10):e12515. Searles SC, Chen WS, Yee JD, Lee P, Lee CK, Caron C, Neto F, Matei I, Lyden D, Bui JD. PMID: 39330930; PMCID: PMC11428867.

12. Evolutionary fingerprint in rodent PD1 confers weakened activity and enhanced tumor immunity compared to human PD1. bioRxiv. 2024 Sep 24. Masubuchi T, Chen L, Marcel N, Wen GA, Caron C, Zhang J, Zhao Y, Morris GP, Chen X, Hedrick SM, Lu LF, Wu C, Zou Z, Bui JD, Hui E. PMID: 39372757; PMCID: PMC11451736.

13. Development of 3D-iNET ORION: a novel, pre-clinical, three-dimensional in vitro cell model for modeling human metastatic neuroendocrine tumor of the pancreas. Hum Cell. 2024 Sep; 37(5):1593-1601. Strnadel J, Valasek MA, Lin GY, Lin H, Tipps AMP, Woo SM, Fujimura K, Wang H, Choi S, Bui J, Hermosillo C, Jepsen K, Navarro MR, Kelber JA, Klemke RL, Bouvet M. PMID: 39103560; PMCID: PMC11341600.

14. A cell-level discriminative neural network model for diagnosis of blood cancers. Bioinformatics. 2023 10 03; 39(10). Robles EE, Jin Y, Smyth P, Scheuermann RH, Bui JD, Wang HY, Oak J, Qian Y. PMID: 37756695; PMCID: PMC10563151.

15. cis-B7:CD28 interactions at invaginated synaptic membranes provide CD28 co-stimulation and promote CD8+ T cell function and anti-tumor immunity. Immunity. 2023 06 13; 56(6):1187-1203.e12. Zhao Y, Caron C, Chan YY, Lee CK, Xu X, Zhang J, Masubuchi T, Wu C, Bui JD, Hui E. PMID: 37160118; PMCID: PMC10330546.

16. Dual receptor T cells mediate effective antitumor immune responses via increased recognition of tumor antigens. J Immunother Cancer. 2023 05; 11(5). Jang HJ, Caron C, Lee CK, Wang L, Jama B, Bui JD, Morris GP. PMID: 37188395; PMCID: PMC10186424.

17. CTLA4 depletes T cell endogenous and trogocytosed B7 ligands via cis-endocytosis. J Exp Med. 2023 07 03; 220(7). Xu X, Dennett P, Zhang J, Sherrard A, Zhao Y, Masubuchi T, Bui JD, Chen X, Hui E. PMID: 37042938; PMCID: PMC10103642.

18. A cell-level discriminative neural network model for diagnosis of blood cancers. medRxiv. 2023 Feb 10. Robles EE, Jin Y, Smyth P, Scheuermann RH, Bui JD, Wang HY, Oak J, Qian Y. PMID: 36798344; PMCID: PMC9934808.

19. SnapShot: Cancer immunoediting. Cell. 2022 10 13; 185(21):4038-4038.e1. Varanasi SK, Kaech SM, Bui JD. PMID: 36240741.

20. Lymphatic-preserving treatment sequencing with immune checkpoint inhibition unleashes cDC1-dependent antitumor immunity in HNSCC. Nat Commun. 2022 07 25; 13(1):4298. Saddawi-Konefka R, O’Farrell A, Faraji F, Clubb L, Allevato MM, Jensen SM, Yung BS, Wang Z, Wu VH, Anang NA, Msari RA, Schokrpur S, Pietryga IF, Molinolo AA, Mesirov JP, Simon AB, Fox BA, Bui JD, Sharabi A, Cohen EEW, Califano JA, Gutkind JS. PMID: 35879302; PMCID: PMC9314425.